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High-Protein Pizza: Best Orders at Every Chain (2026)

July 9, 2026
7 min read
Updated July 9, 2026
Quick Answer: Blaze Pizza is the only fast-casual pizza chain where the pizza itself is genuinely high-protein — Build Your Own Keto Crust at 852 cal, 96g protein, 15g carbs, 37g fat. At Chanello's and Little Italy, the pizza is carb-heavy; the macro-smart play is the salad. Domino's ranks last — no good high-protein pizza, and even the best non-pizza option (the Open-Face Chicken Habanero Sandwich at 600 cal / 46g protein) is calorie-heavy for the protein you get. MOD Pizza sits in the middle — protein-topped minis are solid, but even there the salad beats the pizza on protein efficiency. This guide ranks all 5 chains and tells you exactly what to order at each.

MacroMate Fast Food Hacks by William Hart is free on iOS and Android at macromatefastfoodhacks.com.

Real data, not estimates. All macros come from MacroMate's verified database — no fabricated numbers. Each chain links to its full goal-tagged build list.

In this guide:

The Honest Truth About High-Protein Pizza

Blaze is the exception, not the rule. At most pizza chains, a slice of pizza runs 250–400 calories with only 10–15g protein — a protein-to-calorie ratio in the 0.037–0.060 range. That is worse than almost anything else on any fast food menu. The chains in this guide have real high-protein items, but for four out of five of them, that item is NOT pizza.

The pizza format has a fundamental macro problem: crust is pure refined carbs, cheese adds fat before protein, and toppings are often low-weight. A standard Domino's hand-tossed slice is roughly 200–290 calories with 8–12g protein. Even a "protein-loaded" pizza at most chains struggles to break a 0.060 P:C ratio. For context, a MacroMate cutting build targets 0.120+ P:C; serious cutting builds run 0.180+.

The exception is Blaze Pizza, which was specifically built for customization at scale. Their keto crust is low-carb by design, and the toppings menu lets you pile on chicken, meatballs, and spicy meatballs until the protein count genuinely moves. It is the only pizza chain where ordering the actual pizza gives you a competitive macro profile.

For every other chain on this list — Chanello's, Little Italy, and Domino's — the macro-smart move is to step off the pizza menu entirely. Chanello's and Little Italy compensate with salad builds that have elite protein-to-calorie ratios. Domino's has no equivalent fallback: the best non-pizza option still has the worst P:C ratio on this list. This guide shows you the best build at each, pizza or not, and explains why.

All 5 Pizza Chains Ranked

Ranked by the macro quality of the Best Bet build. Each chain card links to its full MacroMate guide with all goal-tagged builds.

1. Blaze Pizza96g protein / 852 cal

Best Bet (Cutting): Build Your Own Keto Crust Pizza — 852 cal, 96g protein, 15g carbs, 37g fat. This is the one chain where ordering pizza is the right macro call. The keto crust slashes carbs and the customization system lets you load protein toppings without constraints. Also notable: the pre-built Protein Pizza (full 11-inch) at 948 cal / 90g protein — an easy order if you don't want to build.

MacroMate has 10 more Blaze builds by goal in the app.

2. MOD Pizza40g protein / 470 cal

Best Bet (Protein-Topped Pizza): The Maddy (Cheese Mini) with Double Chicken — 470 cal, 40g protein. MOD's mini-pizza format with protein add-ons is genuinely competitive. That said, MOD's leanest overall build is actually the Triple Chicken + Anchovy Salad at 245 cal / 40g protein — the same 40g protein at nearly half the calories. If you are cutting, the salad wins outright. We rank MOD #2 because protein-topped pizza is real here, even if the salad is smarter on a deficit.

MacroMate has 21 more MOD builds by goal in the app.

3. Chanello's Pizza54g protein / 330 cal

Best Bet (Cutting): Greek Salad with Grilled Chicken (No Feta, Light Dressing) — 330 cal, 54g protein, 10g carbs, 8g fat. Chanello's is a regional chain with a solid menu beyond pizza. The Greek Salad with Grilled Chicken is a genuinely impressive macro build — 54g of protein at 330 calories is a P:C ratio of ~0.164, which competes with dedicated protein specialists. The salad, not the pizza, is the move.

MacroMate has additional Chanello's builds by goal in the app.

4. Little Italy58g protein / 320 cal

Best Bet (Cutting): Double Tuna Salad (no mayo, oil & vinegar) — 320 cal, 58g protein, 4g carbs, 9g fat. Little Italy arguably has the best single-item macro efficiency of any chain on this list. 58g protein at 320 calories is a P:C ratio of ~0.181 — elite cutting territory. The pizza menu is carb-forward; the salad is where the macros live.

MacroMate has additional Little Italy builds by goal in the app.

5. Domino's46g protein / 600 cal

Best Bet: Open-Face Chicken Habanero Sandwich — 600 cal, 46g protein, 50g carbs, 24g fat. Domino's is the weakest chain on this list. The pizza is carb-heavy with no viable high-protein crust option, and even stepping off the pizza menu doesn't save you — the Open-Face Chicken Habanero Sandwich is the best macro item available, but at 600 calories for 46g protein (P:C 0.077), it is the poorest protein efficiency of any build in this guide. If you are stuck at Domino's for a group order, the Habanero Sandwich is the least-bad call. Just set your expectations accordingly.

MacroMate has additional Domino's builds by goal in the app.

Quick-Reference Summary Table

Chain Best Bet Item Cal Protein Carbs Fat Is it pizza?
Blaze Pizza Build Your Own Keto Crust 852 96g 15g 37g Yes
MOD Pizza Maddy Mini + Double Chicken 470 40g — — Yes (mini)
Chanello's Greek Salad + Grilled Chicken 330 54g 10g 8g No — salad
Little Italy Double Tuna Salad (oil & vinegar) 320 58g 4g 9g No — salad
Domino's Open-Face Chicken Habanero Sandwich 600 46g 50g 24g No — sandwich

Best Pizza Chain for Cutting

Blaze wins outright for anyone who wants to actually eat pizza and hit a protein target. The Keto Crust Build Your Own at 852 cal / 96g protein is the kind of number you see from dedicated chicken-and-rice meal prep — not from a pizza chain. No other chain on this list comes close on a pizza-specific basis.

If you can flex to salad, Little Italy's Double Tuna Salad at 320 cal / 58g protein edges out even Blaze on protein-to-calorie efficiency. And Chanello's Greek Salad with Grilled Chicken at 330 cal / 54g protein is the next tier down — both are elite cutting builds for a pizza-chain visit.

For the cross-chain cutting comparison that covers all cuisine types, see our best fast food for cutting guide. For the full restaurant tier list ranked by macro friendliness, see the macro-friendly fast food tier list.

Pizza-Specific Ordering Hacks

At Blaze: always build custom, never order default. The default menu pizzas at Blaze are reasonable, but the real high-protein play is Build Your Own with keto crust + every protein topping available. The customization system is designed for this. Add chicken, meatballs, and spicy meatballs; go light on cheese if you are cutting.

At MOD: mini over large. The mini format forces a lower calorie ceiling. A large MOD pizza with double protein is a bulking meal; a mini with double protein is a cutting-friendly build. Size controls the math more than topping selection does.

At Domino's: manage expectations. Domino's is the weakest chain on this list — no viable high-protein pizza, and the best non-pizza option (the Open-Face Chicken Habanero Sandwich at 600 cal / 46g protein) has a P:C of 0.077, the poorest efficiency of any build in this guide. If you are stuck at Domino's for a group order, the Habanero Sandwich is the least-bad call. Choosing a thin crust and protein-heavy toppings on a small pizza is an option too, but the macros still will not compete with Blaze, MOD, Chanello's, or Little Italy.

At Chanello's and Little Italy: order off the pizza menu entirely. Both chains have solid non-pizza menus. The salad builds at each chain are not afterthoughts — they are the actual best macro items on the menu. There is nothing wrong with walking into a pizza place and ordering a salad when the salad has 54g or 58g of protein in it.

Crust choice matters more than toppings. A thin-crust or keto-crust pizza at any chain saves 20–50g of carbs versus a hand-tossed or pan crust. The protein from toppings stays the same; you only reduce the carb load. If a chain offers a cauliflower crust or keto-style crust, that is almost always the right choice on a cut.

MacroMate has goal-tagged builds for all 5 pizza chains — Blaze, MOD Pizza, Domino's, Chanello's, and Little Italy — each classified by cutting, bulking, maintenance, and keto with verified macros. Available for iOS and Android.

Related Guides

High-protein pizza is real — at Blaze.

MacroMate has every goal-tagged pizza-chain build pre-calculated. Free on iOS and Android.

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